HyCyte® | 海星生物

Positive WB detected in：HL-60 cells, K562, PC-12 cells, U-87 MG cells

Positive IP detected in：——

Positive IHC detected in：human lymphoma tissue, human liver cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Positive IF/ICC detected in：——

Positive FC (Intra) detected in：——

推荐稀释比：应用 推荐稀释比

Western Blot (WB) WB : 1:500-1:3000

Immunohistochemistry (IHC) IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent.

免疫原：Peptide

抗体类别：Polyclonal

产品类型：Antibody

全称：RAB27A, member RAS oncogene family

计算分子量：25 kDa

观测分子量：25 kDa

GenBank蛋白编号：NM_004580

基因名称：RAB27A

Gene ID (NCBI)：5873

偶联类型：Unconjugated

形式：Liquid

纯化方式：Antigen affinity purification

UNIPROT ID：«UNIPROT ID»

储存缓冲液：PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.

储存条件：Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.

背景介绍：Rab27A is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27A is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27A is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.

注意事项

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗等用途。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。